Skip to the content

Photochemical DNA cleavage by a Berenil analog

Burr, SJ, Mselati, A and Thomas, EW 2003, 'Photochemical DNA cleavage by a Berenil analog' , Tetrahedron Letters, 44 (39) , pp. 7307-7309.

Full text not available from this repository. (Request a copy)

Abstract

Berenil [bis(4-amidinophenyl)1,3-triazene] is a photostable DNA-binding ligand. We describe here the synthesis of N-(3-hydroxypropyl)-Berenil, which in contrast to Berenil is photosensitive to 360 nm irradiation, behaving as a caged diazonium salt. The 4-amidinobenzenediazonium fragment produced by photolysis induces DNA modification and cleavage.

Item Type: Article
Themes: Subjects / Themes > Q Science > Q Science (General)
Subjects outside of the University Themes
Schools: Colleges and Schools > College of Science & Technology
Colleges and Schools > College of Science & Technology > School of Environment and Life Sciences
Journal or Publication Title: Tetrahedron Letters
Publisher: Elsevier
Refereed: Yes
ISSN: 00404039
Depositing User: H Kenna
Date Deposited: 08 Aug 2007 13:45
Last Modified: 20 Aug 2013 16:45
URI: http://usir.salford.ac.uk/id/eprint/184

Actions (login required)

Edit record (repository staff only)