Skip to the content

Drug-induced supersensitivity psychosis revisited: characteristics of relapse in treatment-compliant patients

Fallon, P, Dursun, S and Deakin, B 2012, 'Drug-induced supersensitivity psychosis revisited: characteristics of relapse in treatment-compliant patients' , Therapeutic Advances in Psychopharmacology, 2 (1) , pp. 13-22.

[img] PDF - Published Version
Restricted to Repository staff only

Download (408kB)

    Abstract

    Background: An association between abnormal involuntary movements and psychotic relapse was previously reported in a group of patients compliant with antipsychotic medication (Fallon and Dursun 2011). This was interpreted as the presence of an antipsychotic medication-induced supersensitivity psychosis. Method: From the results of that study and the Chouinard diagnostic criteria for supersensitivity psychosis an abbreviated diagnostic checklist was developed to identify the phenomenon. In the present study the checklist was used on a larger sample of medication-compliant individuals experiencing a psychotic relapse. Results: The checklist demonstrated its utility by identifying a cause of relapse in 70% (29/41) of patients. Furthermore, it identified the presence of supersensitivity psychosis in 39% (16/41) of patients. This study also replicated a number of findings from the previous paper supporting the idea that supersensitivity psychosis is one cause of relapse in psychosis. Discussion: These results suggested that clinicians should exercise caution in prescribing and may have to augment treatment with other agents or switch to low dopamine-affinity antipsychotics.

    Item Type: Article
    Uncontrolled Keywords: supersensitivity psychosis, relapse, diagnostic checklist
    Themes: Health and Wellbeing
    Schools: Colleges and Schools > College of Health & Social Care
    Colleges and Schools > College of Health & Social Care > School of Nursing, Midwifery, Social Work & Social Sciences > Centre for Nursing, Midwifery & Social Work Research
    Colleges and Schools > College of Health & Social Care > School of Nursing, Midwifery, Social Work & Social Sciences
    Journal or Publication Title: Therapeutic Advances in Psychopharmacology
    Publisher: Sage Publications
    Refereed: Yes
    ISSN: 2045-1253
    Depositing User: H Kenna
    Date Deposited: 08 Oct 2012 14:30
    Last Modified: 20 Aug 2013 18:34
    URI: http://usir.salford.ac.uk/id/eprint/26996

    Document Downloads

    More statistics for this item...

    Actions (login required)

    Edit record (repository staff only)