Validation of GDI, GPS and GVS for use in parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa
Specialli, DS, Correa, JCF, Luna, NM, Brant, R, Greve, JMD, de Godoy, W, Baker, Richard and Lucareli, PRG 2014, 'Validation of GDI, GPS and GVS for use in parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa' , Gait and Posture, 39 (4) , pp. 1142-1145.
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The Gait Deviation Index (GDI), Gait Profile Score (GPS) and Gait Variable Scores (GVSs) have been proposed as measures of gait quality and validated for use with children with cerebral palsy. The aim of this study was to extend this validation to people with Parkinson's disease by evaluating the effects of subthalamic deep brain stimulation and levodopa on gait. 16 participants had their gait evaluated with stimulation, medication or a combination of both. The Unified Parkinson's Disease Rating Scale (UPDRS) showed statistically significant differences in agreement with previous studies. The GPS and GDI showed similar treatment effects as did GVS for hip and knee flexion/extension, as assessed with Cohen's d where medium or large. Overall the results suggest that these gait indices are sensitive to treatment in this group of patients and that their use in groups other than children with cerebral palsy is valid.
|Themes:||Health and Wellbeing|
|Schools:||Schools > School of Health Sciences > Centre for Health Sciences Research
Schools > School of Health Sciences
|Journal or Publication Title:||Gait and Posture|
|Funders:||Non funded research|
|Depositing User:||Prof Richard Baker|
|Date Deposited:||28 Mar 2014 17:46|
|Last Modified:||30 Nov 2015 23:42|
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