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Validation of GDI, GPS and GVS for use in parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa

Specialli, DS, Correa, JCF, Luna, NM, Brant, R, Greve, JMD, de Godoy, W, Baker, Richard and Lucareli, PRG 2014, 'Validation of GDI, GPS and GVS for use in parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa' , Gait and Posture, 39 (4) , pp. 1142-1145.

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Abstract

The Gait Deviation Index (GDI), Gait Profile Score (GPS) and Gait Variable Scores (GVSs) have been proposed as measures of gait quality and validated for use with children with cerebral palsy. The aim of this study was to extend this validation to people with Parkinson's disease by evaluating the effects of subthalamic deep brain stimulation and levodopa on gait. 16 participants had their gait evaluated with stimulation, medication or a combination of both. The Unified Parkinson's Disease Rating Scale (UPDRS) showed statistically significant differences in agreement with previous studies. The GPS and GDI showed similar treatment effects as did GVS for hip and knee flexion/extension, as assessed with Cohen's d where medium or large. Overall the results suggest that these gait indices are sensitive to treatment in this group of patients and that their use in groups other than children with cerebral palsy is valid.

Item Type: Article
Themes: Health and Wellbeing
Schools: Schools > School of Health Sciences > Centre for Health Sciences Research
Schools > School of Health Sciences
Journal or Publication Title: Gait and Posture
Publisher: Elsevier
Refereed: Yes
ISSN: 1879-2219
Related URLs:
Funders: Non funded research
Depositing User: Prof Richard Baker
Date Deposited: 28 Mar 2014 17:46
Last Modified: 30 Nov 2015 23:42
URI: http://usir.salford.ac.uk/id/eprint/30981

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