Mastin, A, Van Kesteren, F, Torgerson, P, Zaidanov, I, Rogan, MT and Craig, PS 2015, 'Investigation of risk factors for Echinococcus coproantigen positivity in dogs in the Alay valley, Kyrgyzstan' , Journal of Helminthology, 89 , pp. 655-663.
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Echinococcosis caused by the zoonotic cestodes Echinococcus granulosus (sensu lato) and Echinococcus multilocularis is highly endemic in the Central Asian Republic of Kyrgyzstan, and is increasingly being identified as public health problem especially amongst pastoral communities. As domestic dogs are considered to be the main source of human infection in these communities, the identification of potential transmission pathways can be of use when considering implementing a control scheme for echinococcosis. The current report describes the results of an analytic study of canine echinococcosis (based on the results of coproantigen ELISA testing) in the Alay valley of southern Kyrgyzstan prior to the commencement of a praziquantel dosing scheme amongst dogs. A logistic regression model using a form of Bayes modal estimation was used to identify possible risk factors for coproantigen positivity, and the output was interpreted in a Bayesian context (posterior distributions of the coefficients of interest). The study found that sheepdogs had lower odds of coproantigen positivity, as did households with donkeys, some knowledge of echinococcosis, and which did not engage in home slaughtering. There was no evidence of an association between free roaming or previous praziquantel dosing and coproantigen positivity, as has been found in previous studies. Possible reasons for these findings are discussed and suggestions made for further work.
|Schools:||Schools > School of Environment and Life Sciences > Ecosystems and Environment Research Centre|
|Journal or Publication Title:||Journal of Helminthology|
|Publisher:||CAB International Publishing|
|Depositing User:||MT Rogan|
|Date Deposited:||11 Jun 2015 15:37|
|Last Modified:||18 Mar 2016 18:06|
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