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A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice

Goodhead, I, Archibald, A, Amwayi, P, Brass, A, Gibson, J, Hall, N, Hughes, M, Limo, M, Iraqi, F and Kemp, SJ 2010, 'A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice' , PLoS Neglected Tropical Diseases, 4 (11) , e880-e880.

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Abstract

African trypanosomes are protozoan parasites that cause “sleeping sickness” in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in two independent crosses between susceptible A/J and BALB/c mice, and the resistant C57BL/6. These were designated Tir1, Tir2 and Tir3 for Trypanosoma infection response, and range in size from 0.9–12 cM.

Item Type: Article
Additional Information: Unmapped bibliographic data: Y1 - 2010/// [EPrints field already has value set]
Themes: Subjects outside of the University Themes
Schools: Schools > School of Environment and Life Sciences > Ecosystems and Environment Research Centre
Journal or Publication Title: PLoS Neglected Tropical Diseases
Publisher: Public Library of Science
Refereed: Yes
ISSN: 1935-2727
Related URLs:
Funders: Royal Society Wolfson Merit, Medical Research Council (MRC), University of Liverpool funded Studentship, Wellcome Trust
Depositing User: Dr Ian Goodhead
Date Deposited: 23 Sep 2015 17:02
Last Modified: 23 Sep 2015 17:02
URI: http://usir.salford.ac.uk/id/eprint/36289

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