Metabolic asymmetry in cancer : a “balancing act” that promotes tumor growth
Martinez-Outschoorn, UE, Sotgia, F and Lisanti, MP 2014, 'Metabolic asymmetry in cancer : a “balancing act” that promotes tumor growth' , Cancer Cell, 26 (1) , pp. 5-7.
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Profound metabolic differences between cancer cells and fibroblasts promote tumorigenesis. A study by Valencia and colleagues in this issue of Cancer Cell supports this assertion. They observed that metabolic asymmetry in prostate tumors drives aggressive disease with high p62 in anabolic cancer cells, but loss of p62 in catabolic fibroblasts.
|Schools:||Schools > School of Environment and Life Sciences > Biomedical Research Centre|
|Journal or Publication Title:||Cancer Cell|
|Funders:||Funder not known|
|Depositing User:||F Sotgia|
|Date Deposited:||05 Jul 2016 09:51|
|Last Modified:||17 Oct 2016 12:35|
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