Brachial artery modifications to blood flow-restricted handgrip training and detraining

Hunt, JEA, Walton, LA and Ferguson, RA 2011, 'Brachial artery modifications to blood flow-restricted handgrip training and detraining' , Journal of Applied Physiology, 112 (6) , pp. 956-961.

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Abstract

Low load resistance training with blood flow restriction (BFR) can increase muscle size and strength, but the implications on the conduit artery are uncertain. We examined the effects of low-load dynamic handgrip training with and without BFR, and detraining, on measures of brachial artery function and structure. Nine male participants (26 ± 4 yr, 178 ± 3 cm, 78 ± 10 kg) completed 4 wk (3 days/wk) of dynamic handgrip training at 40% 1 repetition maximum (1RM). In a counterbalanced manner, one forearm trained under BFR (occlusion cuff at 80 mmHg) and the other under nonrestricted (CON) conditions. Brachial artery function [flow-mediated dilation (FMD)] and structure (diameter) were assessed using Doppler ultrasound. Measurements were made before training (pretraining), after training (posttraining), and after 2-wk no training (detraining). Brachial artery diameter at rest, in response to 5-min ischemia (peak diameter), and ischemic exercise (maximal diameter) increased by 3.0%, 2.4%, and 3.1%, respectively, after BFR training but not after CON. FMD did not change at any time point in either arm. Vascular measures in the BFR arm returned to baseline after 2 wk detraining with no change after CON. The data demonstrate that dynamic low-load handgrip training with BFR induced transient adaptations to conduit artery structure but not function.

Item Type: Article
Schools: Schools > School of Health Sciences > Centre for Health Sciences Research
Journal or Publication Title: Journal of Applied Physiology
Publisher: American Physiological Society
ISSN: 8750-7587
Depositing User: LA Walton
Date Deposited: 20 Jul 2017 15:06
Last Modified: 09 Aug 2017 21:20
URI: http://usir.salford.ac.uk/id/eprint/43114

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