Wilkinson, JA ORCID: https://orcid.org/0000-0003-1300-6017, Rossington, SB, Leonard, J and Hussain, N
2004,
'Asymmetric alkylation of diphenylmethane derivatives using (-)-sparteine'
, Tetrahedron Letters, 45 (6)
, pp. 1191-1193.
Official URL: http://dx.doi.org/10.1016/j.tetlet.2003.11.138
Abstract
Alkylation of 2-oxygenated diphenylmethane derivatives using sec-butyllithium and (−)-sparteine gave enantiomeric excesses of up to 60% with allyl bromide but alkylations with methyl electrophiles were poorly selective. When compounds with a free hydroxy in the 2-position were alkylated the selectivity was reversed.
Item Type: | Article |
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Themes: | Subjects / Themes > Q Science > Q Science (General) Subjects / Themes > Q Science > QD Chemistry Subjects outside of the University Themes |
Schools: | Schools > School of Environment and Life Sciences Schools > School of Environment and Life Sciences > Biomedical Research Centre |
Journal or Publication Title: | Tetrahedron Letters |
Publisher: | Elsevier |
Refereed: | Yes |
ISSN: | 00404039 |
Depositing User: | H Kenna |
Date Deposited: | 08 Aug 2007 14:07 |
Last Modified: | 27 Aug 2021 21:59 |
URI: | http://usir.salford.ac.uk/id/eprint/189 |
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