Asymmetric alkylation of diarylmethane derivatives

Wilkinson, JA ORCID:, Rossington, SB, Ducki, S, Leonard, J and Hussain, N 2006, 'Asymmetric alkylation of diarylmethane derivatives' , Tetrahedron, 62 (8) , pp. 1833-1844.

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Deprotonation–alkylation of prochiral diarylmethane substrates using sec-BuLi and (−)-sparteine has been carried out in excellent yields and up to 94% ee. A variety of enantioselective alkylations, silylations and stannylations have been performed on four different diarylmethanes. Surrogates for (+)-sparteine have also been applied in this study including a novel surrogate.

Item Type: Article
Themes: Subjects / Themes > Q Science > Q Science (General)
Subjects / Themes > Q Science > QD Chemistry
Subjects outside of the University Themes
Schools: Schools > School of Environment and Life Sciences
Schools > School of Environment and Life Sciences > Biomedical Research Centre
Journal or Publication Title: Tetrahedron
Publisher: Elsevier
Refereed: Yes
ISSN: 00404020
Depositing User: H Kenna
Date Deposited: 08 Aug 2007 14:24
Last Modified: 27 Aug 2021 21:59

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