Power output and muscle myosin heavy chain composition in young and elderly men

Pearson, S ORCID: https://orcid.org/0000-0003-1503-5452, Cobbold, M, Orrell, RW and Harridge, SDR 2006, 'Power output and muscle myosin heavy chain composition in young and elderly men' , Medicine & Science in Sports & Exercise, 38 (9) , pp. 1601-1607.

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Purpose: Aging is associated with a decline in muscle volume, power output, and the velocity at which peak power (Vopt) occurs. The current study aimed to examine the relationship between lower-limb power output characteristics, muscle myosin heavy chain (MHC) composition, and lean limb volume. Methods: Lower-limb power output during repeated efforts on an inertial sprint cycle and single-leg thrusts on the modified Nottingham power rig was studied in seven young and seven old males in relation to muscle MHC isoform composition of the vastus lateralis. Results: Older subjects produced significantly lower power outputs and Vopt under all conditions (P < 0.01) and had lower proportions of fast MHC isoforms (P < 0.05). Peak power output during cycling was significantly related to lower-limb lean volume (r = 0.92, P < 0.05), whereas Vopt during sprint cycling was closely related to vastus lateralis MHC-II composition (r = 0.80, P < 0.05). Conclusions: These results provide further evidence of the importance of fast myosin isoform composition in the maintenance of dynamic muscle function in later life and particularly for maximal cycling performance.

Item Type: Article
Themes: Subjects / Themes > R Medicine > R Medicine (General)
Health and Wellbeing
Schools: Schools > School of Health and Society > Centre for Health Sciences Research
Journal or Publication Title: Medicine & Science in Sports & Exercise
Publisher: American College of Sports Medicine
Refereed: Yes
ISSN: 0195-9131
Related URLs:
Funders: Wellcome Trust
Depositing User: H Kenna
Date Deposited: 09 Aug 2007 13:46
Last Modified: 27 Aug 2021 21:59
URI: http://usir.salford.ac.uk/id/eprint/225

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