Pearson, S 
ORCID: https://orcid.org/0000-0003-1503-5452, Cobbold, M, Orrell, RW and Harridge, SDR
2006,
'Power output and muscle myosin heavy chain composition in young and elderly men'
, Medicine & Science in Sports & Exercise, 38 (9)
, pp. 1601-1607.
Abstract
Purpose: Aging is associated with a decline in muscle volume, power output, and the velocity at which peak power (Vopt) occurs. The current study aimed to examine the relationship between lower-limb power output characteristics, muscle myosin heavy chain (MHC) composition, and lean limb volume. Methods: Lower-limb power output during repeated efforts on an inertial sprint cycle and single-leg thrusts on the modified Nottingham power rig was studied in seven young and seven old males in relation to muscle MHC isoform composition of the vastus lateralis. Results: Older subjects produced significantly lower power outputs and Vopt under all conditions (P < 0.01) and had lower proportions of fast MHC isoforms (P < 0.05). Peak power output during cycling was significantly related to lower-limb lean volume (r = 0.92, P < 0.05), whereas Vopt during sprint cycling was closely related to vastus lateralis MHC-II composition (r = 0.80, P < 0.05). Conclusions: These results provide further evidence of the importance of fast myosin isoform composition in the maintenance of dynamic muscle function in later life and particularly for maximal cycling performance.
| Item Type: | Article |
|---|---|
| Themes: | Subjects / Themes > R Medicine > R Medicine (General) Health and Wellbeing |
| Schools: | Schools > School of Health and Society > Centre for Health Sciences Research |
| Journal or Publication Title: | Medicine & Science in Sports & Exercise |
| Publisher: | American College of Sports Medicine |
| Refereed: | Yes |
| ISSN: | 0195-9131 |
| Related URLs: | |
| Funders: | Wellcome Trust |
| Depositing User: | H Kenna |
| Date Deposited: | 09 Aug 2007 13:46 |
| Last Modified: | 27 Aug 2021 21:59 |
| URI: | http://usir.salford.ac.uk/id/eprint/225 |
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