Coward, J ORCID: https://orcid.org/0000-0002-3059-0975, Lawson, R, Kane, T, Elias, M, Howes, A, Birchall, J and Hogg, P
ORCID: https://orcid.org/0000-0002-6506-0827
2014,
'Multi-centre analysis of incidental findings on low-resolution CT attenuation correction images'
, British Journal of Radiology, 87 (1042)
.
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Abstract
Objective: To review new incidental findings detected on
low-resolution CT attenuation correction (CTAC) images acquired
during single-photon emission CT (SPECT-CT) myocardial
perfusion imaging (MPI) and to determine whether
the CTAC images had diagnostic value and warrant reporting.
Methods: A multicentre study was performed in four UK
nuclear medicine departments. CTAC images acquired
as part of MPI performed using SPECT were evaluated to
identify incidental findings. New findings considered to
be clinically significant were evaluated further. Positive
predictive value (PPV) was determined at the time of
definitive diagnosis.
Results: Of 1819 patients studied, 497 (27.3%) had a
positive CTAC finding. 51 (2.8%) patients had findings
that were clinically significant at the time of the CTAC
report and had not been previously diagnosed. Only
four (0.2%) of these were potentially detrimental to
patient outcome.
Conclusion: One centre had a PPV of 0%, and the study
suggests that these CTAC images should not be reported.
Two centres with more modern equipment had low
PPVs of 0% and 6%, respectively, and further research is
suggested prior to drawing a conclusion. The centre with
best quality CT had a PPV of 67%, and the study suggests
that CTAC images from this equipment should be reported.
Advances in knowledge: This study is unique compared
with previous studies that have reported only the potential
to identify incidental findings on low-resolution CT images.
This study both identifies and evaluates new clinically
significant incidental findings, and it demonstrates that
the benefit of reporting the CTAC images depends on
the type of equipment used.
Item Type: | Article |
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Themes: | Health and Wellbeing |
Schools: | Schools > School of Health and Society > Centre for Health Sciences Research |
Journal or Publication Title: | British Journal of Radiology |
Publisher: | British Institute of Radiology |
Refereed: | Yes |
ISSN: | 0007-1285 |
Related URLs: | |
Funders: | Non funded research |
Depositing User: | P Hogg |
Date Deposited: | 19 Sep 2014 16:50 |
Last Modified: | 19 Nov 2018 10:26 |
URI: | http://usir.salford.ac.uk/id/eprint/32819 |
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