Asymmetric synthesis of diarylmethane derivatives by dynamic kinetic resolution

Gooch, LM, Rossington, SB and Wilkinson, JA ORCID: https://orcid.org/0000-0003-1300-6017 2015, 'Asymmetric synthesis of diarylmethane derivatives by dynamic kinetic resolution' , Tetrahedron Letters, 56 (26) , pp. 4025-4027.

PDF - Published Version Restricted to Repository staff only Download (618kB) | Request a copy

Abstract

Asymmetric allylation of ortho-methoxydiphenylmethane has been carried out with high yields and ee of up to 94% using the chiral ligand (−)-sparteine as an additive. Results of reactions performed under various conditions suggest that a dynamic kinetic resolution of two rapidly interconverting diastereomeric complexes is occurring.

Item Type:	Article
Themes:	Subjects outside of the University Themes
Schools:	Schools > School of Environment and Life Sciences > Biomedical Research Centre
Journal or Publication Title:	Tetrahedron Letters
Publisher:	Elsevier
Refereed:	Yes
ISSN:	0040-4039
Related URLs:	Publication
Funders:	Kidscan
Depositing User:	JA Wilkinson
Date Deposited:	01 Jul 2015 11:57
Last Modified:	22 Jan 2020 12:00
URI:	http://usir.salford.ac.uk/id/eprint/35697

Actions (login required)

Edit record (repository staff only)