Asymmetric synthesis of diarylmethane derivatives by dynamic kinetic resolution

Gooch, LM, Rossington, SB and Wilkinson, JA ORCID: 2015, 'Asymmetric synthesis of diarylmethane derivatives by dynamic kinetic resolution' , Tetrahedron Letters, 56 (26) , pp. 4025-4027.

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Asymmetric allylation of ortho-methoxydiphenylmethane has been carried out with high yields and ee of up to 94% using the chiral ligand (−)-sparteine as an additive. Results of reactions performed under various conditions suggest that a dynamic kinetic resolution of two rapidly interconverting diastereomeric complexes is occurring.

Item Type: Article
Themes: Subjects outside of the University Themes
Schools: Schools > School of Environment and Life Sciences > Biomedical Research Centre
Journal or Publication Title: Tetrahedron Letters
Publisher: Elsevier
Refereed: Yes
ISSN: 0040-4039
Related URLs:
Funders: Kidscan
Depositing User: JA Wilkinson
Date Deposited: 01 Jul 2015 11:57
Last Modified: 15 Feb 2022 19:34

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