The role of temperate bacteriophages in bacterial infection

Davies, EV, Winstanley, C, Fothergill, JL and James, C ORCID: 2016, 'The role of temperate bacteriophages in bacterial infection' , FEMS Microbiology Letters, 363 (5) , fnw015.

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Bacteriophages are viruses that infect bacteria. There are an estimated 1031 phage on the planet, making them the most abundant form of life. We are rapidly approaching the centenary of their identification, and yet still have only a limited understanding of their role in the ecology and evolution of bacterial populations. Temperate prophage carriage is often associated with increased bacterial virulence. The rise in use of technologies, such as genome sequencing and transcriptomics, has highlighted more subtle ways in which prophages contribute to pathogenicity. This review discusses the current knowledge of the multifaceted effects that phage can exert on their hosts and how this may contribute to bacterial adaptation during infection.

Item Type: Article
Schools: Schools > School of Environment and Life Sciences
Journal or Publication Title: FEMS Microbiology Letters
Publisher: Oxford University Press
ISSN: 1574-6968
Related URLs:
Funders: Wellcome Trust, Leverhulme Trust
Depositing User: Dr Chloe James
Date Deposited: 19 Apr 2016 12:28
Last Modified: 16 Feb 2022 17:47

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