Metabolic asymmetry in cancer : a “balancing act” that promotes tumor growth

Martinez-Outschoorn, UE, Sotgia, F ORCID: and Lisanti, MP ORCID: 2014, 'Metabolic asymmetry in cancer : a “balancing act” that promotes tumor growth' , Cancer Cell, 26 (1) , pp. 5-7.

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Profound metabolic differences between cancer cells and fibroblasts promote tumorigenesis. A study by Valencia and colleagues in this issue of Cancer Cell supports this assertion. They observed that metabolic asymmetry in prostate tumors drives aggressive disease with high p62 in anabolic cancer cells, but loss of p62 in catabolic fibroblasts.

Item Type: Article
Schools: Schools > School of Environment and Life Sciences > Biomedical Research Centre
Journal or Publication Title: Cancer Cell
Publisher: Elsevier
ISSN: 1535-6108
Related URLs:
Funders: Funder not known
Depositing User: F Sotgia
Date Deposited: 05 Jul 2016 09:51
Last Modified: 30 Jul 2020 08:04

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