Nutritional status deterioration occurs frequently during children's ICU stay

Valla, FV ORCID: https://orcid.org/0000-0002-2547-8209, Baudin, F, Gaillard Le Roux, B, Ford-Chessel, C, Gervet, E, Giraud, C, Ginhoux, T, Cour-Andlauer, F, Javouvey, E ORCID: https://orcid.org/0000-0002-2547-8209 and Tume, LN ORCID: https://orcid.org/0000-0002-2547-8209 2019, 'Nutritional status deterioration occurs frequently during children's ICU stay' , Pediatric Critical Care Medicine, 20 (8) , pp. 714-721.

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Abstract

OBJECTIVES: Malnutrition and faltering growth at PICU admission have been related to suboptimal outcomes. However, little is known about nutritional status deterioration during PICU stay, as critical illness is characterized by a profound and complex metabolism shift, which affects energy requirements and protein turnover. We aim to describe faltering growth occurrence during PICU stay. DESIGN: Single-center prospective observational study. SETTING: Twenty-three-bed general PICU, Lyon, France. PATIENTS: All critically ill children 0-18 years old with length of stay longer than 5 days were included (September 2013-December 2015). INTERVENTIONS: Weight and height/length were measured at admission, and weight was monitored during PICU stay, in order to calculate body mass index for age z score. Faltering growth was defined as body mass index z score decline over PICU stay. Children admitted during the first year of the study and who presented with faltering growth were followed after PICU discharge for 3 months. MEASUREMENTS AND MAIN RESULTS: We analyzed 579 admissions. Of them, 10.2% presented a body mass index z score decline greater than 1 SD and 27.8% greater than 0.5. Admission severity risk scores and prolonged PICU stay accounted for 4% of the variability in nutritional status deterioration. Follow-up of post-PICU discharge nutritional status showed recovery within 3 months in most patients. CONCLUSIONS: Nutritional deterioration is frequent and often intense in critically ill children with length of stay greater than 5 days. Future research should focus on how targeted nutritional therapies can minimize PICU faltering growth and improve post-PICU rehabilitation.

Item Type: Article
Schools: Schools > School of Health and Society > Centre for Applied Research in Health, Welfare and Policy
Journal or Publication Title: Pediatric Critical Care Medicine
Publisher: Lippincott, Williams & Wilkins
ISSN: 1529-7535
Related URLs:
Depositing User: Dr Lyvonne Tume
Date Deposited: 11 Sep 2019 10:37
Last Modified: 11 Sep 2019 10:45
URI: http://usir.salford.ac.uk/id/eprint/52193

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