Priorities for nutrition research in pediatric critical care

Tume, LN ORCID:, Valla, FV, Floh, A, Goday, P, Jotterand-Chapparo, C, Larsen, B, Lee, J, Moreno, Y, Pathan, N, Verbruggen, S and Mehta, N 2019, 'Priorities for nutrition research in pediatric critical care' , Journal of Parenteral and Enteral Nutrition, 43 (7) , pp. 853-862.

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Access Information: This is the peer reviewed version of the following article: Tume, L.N., Valla, F.V., Floh, A.A., Goday, P., Jotterand Chaparro, C., Larsen, B., Lee, J.H., Moreno, Y.M.F., Pathan, N., Verbruggen, S. and Mehta, N.M. (2019), Priorities for Nutrition Research in Pediatric Critical Care. Journal of Parenteral and Enteral Nutrition, 43: 853-862., which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.


Background: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. Objective: The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years. Methods: A modified 3-round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Items were ranked on a 5-point Likert scale. Results: Forty-five research topics (with a mean priority score >3(0-5) were identified within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein intake; the role of pharmaco-nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long-termpatient outcomes; and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0-5) were identified as the highest priority for research. Conclusions: This paper has identified important consensus-derived priorities for clinical research in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research funding should target these priority areas and promote an international collaborative approach to research in this field, with a focus on improving relevant patient outcomes.

Item Type: Article
Schools: Schools > School of Health and Society > Centre for Applied Research in Health, Welfare and Policy
Journal or Publication Title: Journal of Parenteral and Enteral Nutrition
Publisher: Wiley
ISSN: 0148-6071
Related URLs:
Depositing User: Dr Lyvonne Tume
Date Deposited: 04 Sep 2019 14:21
Last Modified: 16 Feb 2022 02:36

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