Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window

Martinez Maestro, L ORCID: https://orcid.org/0000-0001-6629-5313, Ramirez-Hernandez, JE, Bodgan, N, Capobianco, JA, Vetrone, F, Garcia Sole, J and Jaque, D 2012, 'Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window' , Nanoscale, 4 (1) , pp. 298-302.

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Abstract

A new approach to deep tissue imaging is presented based on 8 nm CdTe semiconductor quantum dots (QDs). The characteristic 800 nm emission was found to be efficiently excited via two-photon absorption of 900 nm photons. The fact that both excitation and emission wavelengths lie within the "biological window" allows for high resolution fluorescence imaging at depths close to 2 mm. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal sensitivity of CdTe-QDs, one may envisage, in the near future, their use in high resolution deep-tissue thermal imaging.

Item Type:	Article
Schools:	Schools > School of Computing, Science and Engineering
Journal or Publication Title:	Nanoscale
Publisher:	The Royal Society of Chemistry
ISSN:	2040-3364
Related URLs:	Publication
Funders:	Universidad Autonoma de Madrid, Comunidad Autonoma de Madrid, Spanish Ministerio de Educacion y Ciencia, Banco Santander CEAL-UAM, Natural Sciences and Engineering Research Council (NSERC) of Canada, Concordia University Research Chairs
Depositing User:	L Martinez Maestro
Date Deposited:	05 Dec 2019 10:29
Last Modified:	05 Dec 2019 10:29
URI:	http://usir.salford.ac.uk/id/eprint/53351

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