Influence of synthesis conditions on the structure of nickel nanoparticles and their reactivity in selective asymmetric hydrogenation

Arrigo, R ORCID:, Gallarati, S, Schuster, ME, Seymour, J, Gianolio, D, da Silva, I, Callison, J, Feng, H, Proctor, JE ORCID:, Ferrer, P, Venturini, F, Grinter, D and Held, G 2020, 'Influence of synthesis conditions on the structure of nickel nanoparticles and their reactivity in selective asymmetric hydrogenation' , ChemCatChem, 12 (5) , pp. 1491-1503.

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Unsupported and SiO2-supported Ni nanoparticles (NPs), were synthesised via hot-injection colloidal route using oleylamine (OAm) and trioctylphosphine (TOP) as reducing and protective agents, respectively. By adopting a multi-length scale structural characterization, it was found that by changing equivalents of OAM and TOP not only the size of the nanoparticles is affected but also the Ni electronic structure. The synthetized NPs were modified with (R,R)-tartaric acid (TA) and investigated in the asymmetric hydrogenation of methyl acetoacetate to chiral methyl-3-hydroxy butyrate. The comparative analysis of structure and catalytic performance for the synthetized catalysts has enabled us to identify a Ni metallic active surface, whereby the activity increases with the size of the metallic domains. Conversely, at the high conversion obtained for the unsupported NPs no impact of particle size on the selectivity was observed. (R)-selectivity was very high only on catalysts containing positively charged Ni species such as over the SiO2-supported Ni oxide NPs. This work shows that the chiral modification of metallic Ni NPs with TA is insufficient to maintain high selectivity towards the (R)-enantiomer at long reaction time and provide guidance for the engineering of long-term stable enantioselective catalysts.

Item Type: Article
Schools: Schools > School of Environment and Life Sciences > Biomedical Research Centre
Journal or Publication Title: ChemCatChem
Publisher: Wiley
ISSN: 1867-3880
Related URLs:
Funders: Engineering and Physical Sciences Research Council (EPSRC)
Depositing User: USIR Admin
Date Deposited: 02 Jan 2020 15:06
Last Modified: 16 Feb 2022 03:43

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