Prevalence of Fetal Alcohol Spectrum Disorder (FASD) in Greater Manchester, UK : an active case ascertainment study

McCarthy, R ORCID: https://orcid.org/0000-0003-1842-9086, Mukherjee, RAS, Fleming, KM, Green, J, Clayton-Smith, J, Price, AD ORCID: https://orcid.org/0000-0001-6651-7027, Allely, CS ORCID: https://orcid.org/0000-0001-7640-9505 and Cook, PA ORCID: https://orcid.org/0000-0001-6435-8050 2021, 'Prevalence of Fetal Alcohol Spectrum Disorder (FASD) in Greater Manchester, UK : an active case ascertainment study' , Alcoholism: Clinical and Experimental Research Online, 45 (11) , pp. 2271-2281.

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Abstract

Background: Despite high levels of prenatal alcohol exposure in the UK, evidence on the prevalence of fetal alcohol spectrum disorders (FASD) is lacking. This paper reports on FASD prevalence in a small sample of children in primary school.

Methods: A two-phase active case ascertainment study was conducted in three mainstream primary schools in Greater Manchester, UK. Schools were located in areas that ranged from relatively deprived to relatively affluent. Initial screening of children aged 8-9 years used pre-specified criteria for elevated FASD risk (small for age; special educational needs; currently/previously in care; significant social/emotional/mental health symptoms). Screen positive children were invited for detailed ascertainment of FASD using gold standard measures including medical history, facial dysmorphology, neurological impairment, executive function and behavioural difficulties.

Results: Of 220 eligible children, 50 (23%) screened positive and 12% (26/220) proceeded to phase-two assessment. Twenty had a developmental disorder, of which, four had FASD and four were assessed as possible FASD. The crude prevalence rate of FASD in these schools was 1.8% (95%CI: 1.0%,3.4%) and when including possible cases was 3.6% (2.1%,6.3%). None of these children had previously identified with a developmental diagnosis.

Conclusions: FASD was found to be common in these schools, but limitations to the sampling restrict inferences to a population prevalence. Most of these children’s needs had not previously been identified.

Item Type:	Article
Schools:	Schools > School of Health and Society
Journal or Publication Title:	Alcoholism: Clinical and Experimental Research Online
Publisher:	Wiley
ISSN:	0145-6008
Related URLs:	Publication
Funders:	The Greater Manchester Health and Social Care Partnership
Depositing User:	USIR Admin
Date Deposited:	01 Sep 2021 10:50
Last Modified:	15 Feb 2022 16:41
URI:	http://usir.salford.ac.uk/id/eprint/61709

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