Gait alteration due to haemophilic arthropathies in patients with moderate haemophilia.

Fouasson-Chailloux, A ORCID:, Leboeuf, F ORCID:, Maugars, Y, Trossaert, M, Menu, P, Rannou, F, Vinatier, C ORCID:, Guicheux, J, Gross, R and Dauty, M 2022, 'Gait alteration due to haemophilic arthropathies in patients with moderate haemophilia.' , International Journal of Environmental Research and Public Health, 19 (12) , p. 7527.

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Some patients with moderate haemophilia (PWMH) report joint damage potentially responsible for gait disorders. Three-dimensional gait analysis (3DGA) is a relevant tool for the identification of complex musculoskeletal impairment. We performed an evaluation with 3DGA of 24 PWMH aged 44.3 ± 16.1 according to their joint status [Haemophilia Joint Health Score (HJHS) < 10 or HJHS ≥ 10] and assessed the correlation with the radiological and clinical parameters. Sixteen had HJHS < 10 (group 1) and eight had HJHS ≥ 10 (group 2). They were compared to 30 healthy subjects of a normative dataset. Both knee and ankle gait variable scores were increased in group 2 compared to the controls (p = 0.02 and p = 0.04, respectively). The PWMH of group 2 had a significant increase in their stance phase, double support duration, and stride width compared to the controls and group 1 (p < 0.01). Very low correlations were found for the ankle gait variable score with the ankle Pettersson sub-score (r2 = 0.250; p = 0.004) and ankle HJHS sub-score (r2 = 0.150; p = 0.04). For the knee, very low correlation was also found between the knee gait variable score and its HJHS sub-score (r2 = 0.290; p < 0.0001). Patients with moderate haemophilia presented a gait alteration in the case of poor lower limb joint status.

Item Type: Article
Schools: Schools > School of Health and Society
Journal or Publication Title: International Journal of Environmental Research and Public Health
Publisher: MDPI
ISSN: 1661-7827
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SWORD Depositor: Publications Router
Depositing User: Publications Router
Date Deposited: 12 Aug 2022 12:37
Last Modified: 17 Aug 2022 08:02

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