Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases

Gao, J-M ORCID:, Qian, Z-Y, Hide, G ORCID:, Lai, D-H, Lun, Z-R and Wu, Z-D 2020, 'Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases' , Parasitology, 147 (9) , pp. 922-931.

PDF - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0.

Download (2MB) | Preview


Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported cases has fallen to a historically low level. Although fewer than 977 cases were reported in 2018 in endemic countries, HAT is still a public health problem in endemic regions until it is completely eliminated. In addition, almost 150 confirmed HAT cases were reported in non-endemic countries in the last three decades. The majority of non-endemic HAT cases were reported in Europe, United States and South Africa, due to historical alliances, economic links or geographic proximity to disease endemic countries. Furthermore, with the implementation of the “Belt and Road” project, sporadic imported HAT cases have been reported in China as a warning sign of tropical diseases prevention. In this paper, we explore and interpret the data on HAT incidence and find no positive correlation between the number of HAT cases from endemic and non-endemic countries.This data will provide useful information for better understanding the imported cases of HAT globally in the post-elimination phase.

Item Type: Article
Additional Information: ** From PubMed via Jisc Publications Router **Journal IDs: eissn 1469-8161 **Article IDs: pubmed: 32338232; pii: S0031182020000645 **History: published 27-04-2020
Schools: Schools > School of Environment and Life Sciences
Journal or Publication Title: Parasitology
Publisher: Cambridge University Press
ISSN: 0031-1820
Related URLs:
Funders: National Science and Technology Major Project, National Natural Science Foundation
SWORD Depositor: Publications Router
Depositing User: Publications Router
Date Deposited: 11 May 2020 10:31
Last Modified: 16 Feb 2022 04:37

Actions (login required)

Edit record (repository staff only) Edit record (repository staff only)


Downloads per month over past year