World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for studies evaluating the efficacy of parasiticides in reducing the risk of vector-borne pathogen transmission in dogs and cats

Otranto, D, Dantas-Torres, F, Fourie, JJ, Lorusso, V, Varloud, M, Gradoni, L, Drake, J, Geurden, T, Kaminsky, R, Heckeroth, AR, Schunack, B, Pollmeier, M, Beugnet, F and Holdsworth, P 2021, 'World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for studies evaluating the efficacy of parasiticides in reducing the risk of vector-borne pathogen transmission in dogs and cats' , Veterinary Parasitology, 290 , p. 109369.

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Abstract

These guidelines are intended to provide an in-depth review of current knowledge and assist the planning and implementation of studies for evaluating the efficacy of parasiticides in reducing transmission of vector-borne pathogens (VBPs) to dogs and cats. At present, the prevention of VBP transmission in companion animals is generally achieved through the administration of products that can repel or rapidly kill arthropods, thus preventing or interrupting feeding before transmission occurs. The present guidelines complement existing guidelines, which focus on efficacy assessment of parasiticides for the treatment, prevention and control of flea and tick infestations, but also give guidance for studies focused on other vectors (i.e. mosquitoes and phlebotomine sand flies). The efficacy of parasiticides in reducing VBP transmission can be evaluated through laboratory or field studies. As such, the present guidelines provide recommendations for these studies, representing a tool for researchers, pharmaceutical companies and authorities involved in the research, development and registration of products with claims for reducing VBP transmission in dogs and cats, respecting the overall principles of the 3Rs (replacement, reduction and refinement). Gaps in our current understanding of VBP transmission times are herein highlighted and the need for further basic research on related topics is briefly discussed.

Item Type:	Article
Additional Information:	** Article version: AM ** Embargo end date: 31-12-9999 ** From Elsevier via Jisc Publications Router ** Licence for AM version of this article: This article is under embargo with an end date yet to be finalised. **Journal IDs: issn 03044017 **History: issue date 24-01-2021; accepted 19-01-2021
Schools:	Schools > School of Environment and Life Sciences
Journal or Publication Title:	Veterinary Parasitology
Publisher:	Elsevier
ISSN:	0304-4017
Related URLs:	Publication
SWORD Depositor:	Publications Router
Depositing User:	Publications Router
Date Deposited:	11 Feb 2021 09:13
Last Modified:	16 Feb 2022 06:37
URI:	https://usir.salford.ac.uk/id/eprint/59425

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