Approaches to the identification and management of depression in people living with chronic kidney disease: a scoping review of 860 papers

Pearce, C, Hall, N, Hudson, J, Farrington, K, Ryan Tucker, M, Wellsted, D, Jones, J, Sharma, S, Norton, S, Ormandy, P ORCID:, Palmer, N, Quinnell, A, Fitzgerald, L, Griffiths, S and Chilcot, J 2023, 'Approaches to the identification and management of depression in people living with chronic kidney disease: a scoping review of 860 papers' , Journal of Renal Care , pp. 1-11.

PDF - Published Version
Available under License Creative Commons Attribution 4.0.

Download (1MB) | Preview


Background Depression is prevalent across the spectrum of Chronic Kidney Disease and associated with poorer outcomes. There is limited evidence regarding the most effective interventions and care pathways for depression in Chronic Kidney Disease. Objectives To investigate how depression is identified and managed in adults with Chronic Kidney Disease. Design Scoping review. Methods Systematic search of eight databases with pre-defined inclusion criteria. Data relevant to the identification and/or management of depression in adults with Chronic Kidney Disease were extracted. Results Of 2147 articles identified, 860 were included. Depression was most identified using self-report screening tools (n = 716 studies, 85.3%), with versions of the Beck Depression Inventory (n = 283, 33.7%) being the most common. A total of 123 studies included data on the management of depression, with nonpharmacological interventions being more frequently studied (n = 55, 45%). Cognitive Behavioural Therapy (n = 15) was the most common nonpharmacological intervention, which was found to have a significant effect on depressive symptoms compared to controls (n = 10). However, how such approaches could be implemented as part of routine care was not clear. There was limited evidence for antidepressants use in people with Chronic Kidney Disease albeit in a limited number of studies. Conclusions Depression is commonly identified using validated screening tools albeit differences exist in reporting practices. Evidence regarding the management of depression is mixed and requires better-quality trials of both pharmacological and nonpharmacological approaches. Understanding which clinical care pathways are used and their evidence, may help facilitate the development of kidney care specific guidelines for the identification and management of depression.

Item Type: Article
Schools: Schools > School of Health and Society > Centre for Applied Research in Health, Welfare and Policy
Schools > School of Health and Society
Journal or Publication Title: Journal of Renal Care
Publisher: Wiley-Blackwell
ISSN: 1755-6678
Funders: Kidney Research UK and The Stoneygate Trust
Depositing User: Professor Paula Ormandy
Date Deposited: 31 Jan 2023 10:00
Last Modified: 31 Jan 2023 10:00

Actions (login required)

Edit record (repository staff only) Edit record (repository staff only)