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C James

Contact
Biography
My Most Viewed
My Latest

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Contact

Name:

C James

Email:

C.James@salford.ac.uk

Department:

School of Science, Engineering & Environment

Organisation:

School of Environment and Life Sciences, University of Salford

Address:

Peel Building M5 4WT

Country:

profile_image:

Biography

Expertise:

Microbiology, Molecular biology, Bacteriophages, Bacterial Pathogens, Foodborne Pathogens, Pathogenicity, Oral Microbiology, Respiratory Microbiology

Job title:

Senior Lecturer in Medical Microbiology

Biography:

My chief research interests lie in bacterial pathogenicity, development and spread of antibiotic resistance and in how microbial evolution is driven by interaction with microbial communities and their environments. I am particularly interested in Gram-negative bacteria in multi-species biofilms; and bacteriophages. I have worked on molecular aspects of pathogenicity, regulation and antibiotic resistance in Escherichia coli, Porphyromonas gingivalis, Streptococcus gordonii; Enterobacter aerogenes; Pseudomonas aeruginosa; Campylobacter jejuni My research history includes several postdoctoral research positions at the Institute of Infection and Global Health, University of Liverpool, UK; Facultés de Médecine et de Pharmacie, Universite de La Mediterranne, Marseille, France; and the departmenmore...

Qualifications:

BSc Hon's in Medical Microbiology at The University of Edinburgh (1994 to 1998). PhD from the School of Biological Sciences at the University of Liverpool (2003), for work on bacteriophages of E. coli O157.

My Most Viewed

#	Item title
1.	Temperate phages both mediate and drive adaptive evolution in pathogen biofilms	408	200
2.	Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections	367	396
3.	The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria	365	1698
4.	Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa	355	240
5.	The effect of antibiotic treatment on bacteriophage production by a cystic fibrosis epidemic strain of Pseudomonas aeruginosa	344	241
6.	Role of environmental survival in transmission of Campylobacter Jejuni	341	338
7.	The role of temperate bacteriophages in bacterial infection	336	262
8.	How beta-lactam antibiotics enter bacteria: a dialogue with the porins	325	220
9.	50 important research questions in microbial ecology	307	1369
10.	Membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens.	306

My Latest

Gonzalez Tortuero, E ORCID: https://orcid.org/0000-0001-8934-6822, Krishnamurthi, R, Goodhead, IB ORCID: https://orcid.org/0000-0002-3110-9442, Allison, H and James, C ORCID: https://orcid.org/0000-0002-0131-7988 2022, 'Improving phage genome annotation to understand phage biology: the case of Pseudomonas aeruginosa LES prophages' , Access Microbiology, 4 (5) .
Ackers-Johnson, G, Kibombo, D, Kusiima, B, Nsubuga, ML, Kigozi, E, Kajumbula, HM ORCID: https://orcid.org/0000-0002-2075-0007, Kateete, DP, Walwema, R, Ackers, HL ORCID: https://orcid.org/0000-0001-7811-636X, Goodhead, IB ORCID: https://orcid.org/0000-0002-3110-9442, Birtles, RJ ORCID: https://orcid.org/0000-0002-4216-5044 and James, C ORCID: https://orcid.org/0000-0002-0131-7988 2021, 'Antibiotic resistance profiles and population structure of disease-associated Staphylococcus aureus infecting patients in Fort Portal Regional Referral Hospital, Western Uganda' , Microbiology, 167 (5) , 001000.
Goodhead, IB ORCID: https://orcid.org/0000-0002-3110-9442, Ackers, HL ORCID: https://orcid.org/0000-0001-7811-636X, Birtles, RJ ORCID: https://orcid.org/0000-0002-4216-5044 and James, C ORCID: https://orcid.org/0000-0002-0131-7988 2020, 'Antibiotic resistance profiles and population structure of disease-associated Staphylococcus aureus infecting patients in Fort Portal Regional Referral Hospital, Western Uganda' , bioRxiv .
Molitor, A, James, CE ORCID: https://orcid.org/0000-0002-0131-7988, Fanning, S, Pages, JM and Davin-Regli, A 2018, 'Ram locus is a key regulator to trigger multidrug resistance in Enterobacter aerogenes' , Journal of Medical Microbiology, 67 (2) , pp. 148-159.
Bronowski, C, Mustafa, K, Goodhead, IB ORCID: https://orcid.org/0000-0002-3110-9442, James, CE ORCID: https://orcid.org/0000-0002-0131-7988, Nelson, C, Lucaci, A, Wigley, P, Humphrey, TJ, Williams, NJ and Winstanley, C 2017, 'Campylobacter jejuni transcriptome changes during loss of culturability in water' , PLOS ONE, 12 (11) , e0188936.
Antwis, RE ORCID: https://orcid.org/0000-0002-8849-8194, Griffiths, SM, Harrison, XA, Aranega-Bou, P, Arce, A, Bettridge, AS, Brailsford, FL, De Menezes, AB, Devaynes, A, Forbes, KM, Fry, EL, Goodhead, IB ORCID: https://orcid.org/0000-0002-3110-9442, Haskell, E, Heys, C, James, C ORCID: https://orcid.org/0000-0002-0131-7988, Johnston, SR, Lewis, GR, Macey, MC, McCarthy, A, McDonald, JE, Mejia-Florez, NL, O'Brien, D, Orland, C, Pautasso, M, Reid, WDK, Robinson, H, Wilson, K and Sutherland, WJ 2017, '50 important research questions in microbial ecology' , FEMS Microbiology Ecology, 93 (5) .
Davies, E, James, C ORCID: https://orcid.org/0000-0002-0131-7988, Brockhurst, M and Winstanley, C 2017, 'Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model' , BMC Microbiology, 17 (3) .
Davies, E, James, C ORCID: https://orcid.org/0000-0002-0131-7988, Williams, D, O'Brien, S, Fothergill, J, Haldenby, S, Paterson, S, Winstanley, C and Brockhurst, M 2016, 'Temperate phages both mediate and drive adaptive evolution in pathogen biofilms' , Proceedings of the National Academy of Sciences of the United States of America (PNAS), 113 (29) , pp. 8266-8271.
Davies, EV, James, C ORCID: https://orcid.org/0000-0002-0131-7988, Kukavica-Ibrulj, I, Levesque, RC, Brockhurst, MA and Winstanley, C 2016, 'Temperate phages enhance pathogen fitness in chronic lung infection' , ISME Journal, 10 , pp. 2553-2555.
Davies, EV, Winstanley, C, Fothergill, JL and James, C ORCID: https://orcid.org/0000-0002-0131-7988 2016, 'The role of temperate bacteriophages in bacterial infection' , FEMS Microbiology Letters, 363 (5) , fnw015.